Jonathan Mah
I am a computational evolutionary biologist interested in investigating fundamental basic questions regarding mathematical evolution, especially in microbial systems. During my undergraduate studies at the University of Washington, Seattle, I worked in Dr. Jesse Bloom's Lab on experimentally informed codon-selection models for protein evolution in RNA viruses.
Additionally during my undergraduate studies, from June 2019 to August 2019, I worked with Professor Kirk Lohmueller on inferring the distribution of fitness effects in canine evolutionary histories as part of the Bruins-In-Genomics Summer Undergraduate Research Program at UCLA.
In Fall 2020, I started my PhD studies through the Bioinformatics Interdepartmental Program at UCLA. My current research, coadvised by Professor Kirk Lohmueller and Professor Nandita Garud focuses on using and developing statistical methods to analyze genomic variation data through the lens of a summary statistic known as the site frequency spectrum (SFS).
Contact
- E-mail:
jonmah@g.ucla.edu.edu
- Github:
jon-mah
Research
Here are some of the projects I've worked on over the past several years.
The distribution of fitness effects varies phylogenetically across animals.
Meixi Lin, Sneha Chakraborty, Eduardo Amorim, Sergio Nigenda-Morales, Annabel Beichman, Paulina Nunez-Valencia, Jonathan Mah, Jacqueline Robinson, Christopher Kyriazis, Christian Huber, Andrew Webb, Sarah Kocher, Frederick Archer, Andres Moreno-Estrada, Robert Wayne, Kirk Lohmueller.
Manuscript on BioRxiv, currently under review at PLoS Biology.
Inference of the demographic histories and selective effects of human gut commensal microbiota over the course of human history".
Jonathan Mah Kirk Lohmueller, Nandita Garud
Final manuscript publised in Molecular Evolutionar and Biology.
Github repository available here.
Evolutionary consequences of domestication on the selective effects of new amino acid changing mutations in canids.
Eduardo Amorim, Chenlu Di, Meixi Lin, Clare Marsden, Tina Del Carpio, Jonathan Mah, Jacqueline Robinson, Bernard Kim, Jazlyn Mooney, Omar Cornejo
Manuscript on BioRxiv, currently under review at Molecular Biology and Evolution.
Identifying sites under positive selection on viral proteins
Jonathan Mah, Sarah Hilton, Jesse Bloom
Brief CV
- Current: PhD Bioinformatics, UCLA, Expected 2026
- Undergraduate: BS Biochemistry with Honors, Microbiology with Distinction, University of Washington, 2020
I have been fortunate to receive funding support from:
[Download full CV]